Anaconda3 folder / base not a valid Conda folder

I’ve been having issues with my VSCode install not allowing me to set a Python interpreter. I then checked my conda install, and commands such as ‘conda list’ return DirectoryNotACondaEnvironmentErrors. Conda tells me to run ‘conda create’, and points to the correct target directory 'C:\Users\user\AppData\Local\anaconda3, but when I try to run this as a prefix I get a CondaValueError as base is a reserved environment name. I am also unable to un/reinstall conda, as when I attempt to run the uninstaller by any method it fails as it is not run from a valid Conda directory. I had been able to install/update packages until recently, but now I also get a NoBaseEnvironmentError when attempting this.

Does anyone have any advice for ways to reinstall or otherwise fix my conda and VSCode please?